Published on
August 28, 2025

Physical Chemical Engineer with experience in particle engineering

Zerion is a pharmaceutical company enabling the development of novel drug products by improving the solubility and bioavailability of small molecule drugs. Our first drug formulation will reach the market in 2 years and secure regulatory acceptance of our key excipient, the protein beta-lactoglobulin, as a novel pharmaceutical excipient. The manufacturing of our unique Dispersome® formulation requires insights into particle engineering as well as solvent mixing behavior. We aim to improve our current understanding of the manufacturing process, and therefore, are looking for an eager scientist who can take the lead on a particle engineering project for our Dispersome® formulations.

The position

Overall, you will be part of our R&D Department and responsible for development of process understanding and particle engineering for different Dispersome® formulations and preparing those for upscale manufacture. The position will be partly based at our offices in Copenhagen/Denmark and at the facilities of our collaborator in Berlin/Germany.

This includes – without limitation – responsibility for:

  • Hands on development of robust process parameters, including solvent mixing behavior, using a combination of experimental and modelling tools.
  • Assessment and quality control of the amorphous Dispersome® formulations including solid state characterization using XRPD, DSC, TGA as well as dissolution and stability.
  • Definition of critical process and quality parameters and design of process validation protocols.
  • Contribute to establishing full manufacturing processes for final products - in close collaboration with our CMC department as well as third party manufacturers.
  • Design of project protocols with internal and external stakeholders.
  • Technical reports and updates to the ZERION R&D department and management.

Your profile

We are seeking a self-motivated and independent person, with a MSc or PhD degree in pharmacy, physical chemistry, chemical engineering, or similar, having experience from working with particle engineering, fluid dynamics, and/or amorphous formulations. You are flexible working at two different locations in Denmark and Germany.

We would prefer that you have experience with all or most of the following areas:

  • Particle engineering
  • Fluid dynamics and mixing behavior
  • Development of down-streaming processes of amorphous drug delivery systems.
  • Hands-on experience with simulations/modelling
  • Transfer of lab processes to pilot scale and full-scale manufacturing

We expect that you aim at meeting high-quality standards in your work, dedicated to meet deadlines critical to the team and the company.

The opportunity

You will be working closely with the dedicated and innovative colleagues from the R&D and CMC departments at ZERION and our collaborators in Berlin/Germany. We offer a challenging job in an exciting environment where you will be an essential part contributing to our ambitious goal of bringing our novel amorphous formulation technology from our research lab to industrial manufacturing and the market.

  • Please submit your application and CV to Zerion ApS, Fruebjergvej 3, 2100 Copenhagen or by email to kl@zerion.eu, attention Korbinian Löbmann before September 30, 2025.
  • Intended start date on December 1, 2025.
  • If you want to hear more about the position, please contact Korbinian Löbmann, CSO at +45 53 14 55 16

Learn more about what it is like working at Zerion:

https://www.zerion.eu/careers